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雌激素对乳腺纤维囊性增生病的影响各家报道不一。本文综述乳腺纤维囊性增生病妇女体内雌激素及其受体水平、乳腺密度和进行雌激素补充治疗前瞻性随机对照研究的进展。认为只要定期监测,有补充激素指征的乳腺纤维囊性增生病妇女使用雌激素是安全的。
Abstract:The effect of estrogens on fibrocystic breast disease(FBD) are controversial.This review included the advance in the study of concentrations of estrogens and their receptors,mammographic breast density of women with FBD,as well as the impact of different hormone replacement therapy regimens on women with FBD by a prospective,randomized,case-control study.We believed that estrogen replacement therapy is safe for women with FBD,if they are followed-up by mammography or ultrasonography.
[1]Cole P,Elwood JM,Kaplan SD.Incidence rates and risk fac-tors of benign breast neoplasms[J].Am J Epidemiol,1978,108(2):112-120.
[2]Hislop TG,Elwood JM.Risk factors for benign breast dis-ease.A 30 years cohort study[J].Can Med Assoc J,1981,124(3):283-291.
[3]胡虞乾,邓水柱,邱小芬,等.女性乳腺小叶增生症高危因素分析与防治对策[J].广西医学,2002,24(9):1358-1366.
[4]姬霞,冯亚莉.高校女教职工乳腺增生症相关因素分析[J].中国校医,2002,16(3):279-280.
[5]Wu C,Ray RM,Lin MG,et al.A case-control study of riskfactors for fibrocystic breast conditions:shanghai nutritionand breast disease study,China,1995-2000[J].Am J Epide-miol,2004,160(10):945-960.
[6]Berkowitz GS,Kelsey JL,Holford TR,et al.Estrogen re-placement therapy and fibrocystic breast disease in postmeno-pausal women[J].Am J Epidemiol,1985,121(2):238-245.
[7]Trapido EJ,Brinton LA,Schairer C,et al.Estrogen replace-ment therapy and benign breast disease[J].J Natl CancerInst,1984,73(5):1101-1105.
[8]Pastides H,Najjar MA,Kelsey JL.Estrogen replacementtherapy and fibrocystic breast disease[J].Am J Prev Med,1987,3(5):282-286.
[9]Laidlaw IL,Clarke RB,Howell A,et al.The proliferation ofnormal human breast tissue implanted into athymic nude miceis stimulated by estrogen but not progesterone[J].Endocri-nology,1995,136(1):164-171.
[10]邓文慧,陆旭,吴宜勇,等.苯甲酸雌二醇对植入裸鼠体内的人正常乳腺组织的影响[J].中国医学科学院学报,2003,83(5):430-431.
[11]Lundstrom E,wilczek B,Palffy Z,et al.Mammographicbreast density during hormone replacement therapy:effectsof continuous combination,unopposed transdermal and low-potency estrogen regimens[J].Climacteric,2001,4(1):42-48.
[12]Erel CT,Erel G,Seyisoglu H,et al.Mammographic densityincrease in women receiving different hormone replacementregimens[J].Maturitas,2001,40(2):151-157.
[13]Sendag F,Terek MC,Ozsener S,et al.Mammographic den-sity changes during postmenopausal hormone replacementtherapies[J].Fertil Steril,2001,76(3):445-450.
[14]Sieja K,Stanosz S.The concentrations of prolactin and estro-gens in women with fibrocystic changes in the breast[J].Ginekol Pol,2002,73(7):594-599.
[15]Rose DP,Lahti H,Laakso K,et al.Serum and breast ductfluid prolactin and estrogen levels in healthy Finnish andAmerican women and patients with fibrocystic disease[J].Cancer,1986,57(8):1550-1554.
[16]Mustafa IA,Bland KI.Physiologic effects of steroid hor-mones and postmenopausal hormone replacement on the fe-male breast and breast cancer risk[J].Ann Surgery,1998,228(5):638-651.
[17]石晓毅,沈明,王玲娟.非癌性乳腺肿块的雌激素受体表达及其临床意义[J].中国肿瘤临床与康复,2002,9(3):69-70.
[18]Yenen MC,Dede M,Goktolga U,et al.Hormone replace-ment therapy in postmenopausal women with benign fibrocys-tic mastopathy[J].Climacteric,2003,6(2):146-150.
[19]Weissberger AJ,Ho KY,Lazarus L.Contrasting effects oforal and transdermal routes of estrogen replacement therapyon 24-hour growth factor(GH)secretion,insulin-likegrowth factor I,and GH-binding protein in postmenopausalwomen[J].J Clin Endocrinol Metab,1991,72(2):374-381.
[20]Ruan W,Kleinberg DL.Insulin-like growth factor I is essen-tial for terminal end bud formation and ductal morphogenesisduring mammary development[J].Endocrinology,1999,140(11):5057-5081.
[21]Briand P,Lundholt BK,Skouv J,et al.Growth response ofbreast epithelial cells to estrogen is influenced by EGF[J].Mol Cell Endocrinol,1999,153(1-2):1-9.
[22]Pathak DR,Osuch JR,He J.Breast carcinoma etiology[J].Cancer,2000,188[Soppl 5]:1230-1237.
[23]高道利.乳腺癌的病因和预防[J].中国临床医学,1999,6(4):319-320.
[24]李经忠,刘峰,刘正华.乳腺癌的病因学研究现状[J].肿瘤防治研究,2001,28(4):328-330.
基本信息:
中图分类号:R655.8
引用信息:
[1]林芸,孙爱军.乳腺纤维囊性增生病与雌激素的相关性[J].生殖医学杂志,2007(01):56-59.
2007-02-15
2007-02-15