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目的观察地屈孕酮应用于同种免疫型复发性流产的临床效果,为同种免疫型复发性流产寻求可预防的方案。方法 86例同种免疫型复发性流产随机分为两组,观察组43例应用地屈孕酮保胎治疗,对照组43例应用黄体酮保胎治疗,观察两组妊娠结局。结果观察组妊娠成功率86.05%(37/43),显著高于对照组的76.74%(33/43)(P<0.05)。结论地屈孕酮应用于同种免疫型复发性流产患者,妊娠成功率较高,值得临床推广。
Abstract：[1]Kuon RJ,Wallwiener LM,Gemeyer A,et al.Establishment of a standardized immunological diagnostic procedure in RM patients[J].J Reprod Immunol,2012,94:55-57.
[2]Branch DW,Gibson M,Silver RM.Clinical pratice.Recurrent miscarriage[J].N Engl J Med,2010,363:1740-1747.
[3]林其德.复发性流产免疫学诊断和治疗共识[J].生殖医学杂志,2008,17:4-5.
[4]Di Renzo GC,Mattei A,Gojnic M,et al.Progesterone and pregnancy[J].Curr Opin Obstet Gynecol,2005,17:598-600.
[5]Szekeres-Bartho J,Balasch J.Progestagen therapy for recurrent miscarriage[J].Hum Reprod Update,2008,14:27-35.
[6]张建平,林其德,李大金,等.复发性流产的诊断与治疗[J].现代妇产科进展,2006,7:481-491.
[7]Szekeres-Bartho J,Kilar′F,Falkay G,et al.The mechanism of the inhibitory effect of progesterone on lymphocyte cytotoxicity:1.progesterone-treated lymphocytes release a substance inhibiting cytotoxicity and prostaglandin synthesis[J].Am J Repord Immunol Microbiol,1985,9:15-18.
[8]张云霞.地屈孕酮应用于先兆流产的效果观察[J].中国现代医生,2010,48:47.
[9]Raghupathy R,AI Mutawa E,Makhseed M,et al.Redirection of cytokine production by lymphocytes from women with preterm delivery by dydrogesterone[J].Am J Reprod Immunol,2007,58:31-38.
[10]Ghosh S,Chattopadhyay R,Goswami S,et al.Assessment of sub-endometrial blood flow parameters following dydrogesterone and micronized vaginal progesterone administration in women with idiopathic recurrent miscarriage:apilot study[J].J Obstet Gynaecol Res,2014,40:1871-1876.
[11]Parveen F,Faridi RM,Agrawal S,et al.Genetic analysis of eNOS gene polymorphisms in association with recurrent miscarriage among North Indian women[J/OL].Reprod Biomed Online,2011,23:124-131.
[12]张峰,张国英,徐秀华,等.主动免疫联合地屈孕酮治疗复发性流产的临床疗效研究[J].生殖医学杂志,2014,23:320-323.
基本信息:
中图分类号:R714.21
引用信息:
[1]张立岩,周晓.地屈孕酮应用于同种免疫型复发性流产的临床观察[J].生殖医学杂志,2017,26(04):372-374.
2017-04-15
2017-04-15