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先天性肾上腺皮质增生症(congenital adrenal hyperplasia, CAH)是一组由基因突变导致肾上腺皮质激素合成障碍的常染色体隐性遗传病。CAH育龄期女性患者妊娠率及活产率明显下降。本文报道1例失盐型CAH患者经过内分泌科和生殖中心共同治疗,最终行体外受精-胚胎移植后成功妊娠的诊疗过程。
Abstract:[1] Witchel SF.Congenital Adrenal Hyperplasia[J].J Pediatr Adolesc Gynecol,2017,30:520-534.
[2] Bornstein SR,Allolio B,Arlt W,et al.Diagnosis and treatment of primary adrenal insufficiency:an endocrine society clinical practice guideline[J].J Clin Endocrinol Metab,2016,101:364-389.
[3] Badeghiesh A,Ismail S,Baghlaf H,et al.Pregnancy,delivery and neonatal outcomes among women with congenital adrenal hyperplasia:a study of a large US database[J/OL].Reprod Biomed Online,2020,41:1093-1099.
[4] Hagenfeldt K,Janson PO,Holmdahl G,et al.Fertility and pregnancy outcome in women with congenital adrenal hyperplasia due to 21-hydroxylase deficiency[J].Hum Reprod,2008,23:1607-1613.
[5] Bidet M,Bellanné-Chantelot C,Galand-Portier MB,et al.Fertility in women with nonclassical congenital adrenal hyperplasia due to 21-hydroxylase deficiency[J].J Clin Endocrinol Metab,2010,95:1182-1190.
[6] El-Maouche D,Arlt W,Merke DP.Congenital adrenal hyperplasia[J].Lancet,2017,390:2194-2210.
[7] 胡玥玥,徐少元,彭海英,等.先天性肾上腺皮质增生症行体外受精-胚胎移植一例分析及文献复习[J].国际生殖健康/计划生育杂志,2018,37:463-467.
[8] Casteràs A,De Silva P,Rumsby G,et al.Reassessing fecundity in women with classical congenital adrenal hyperplasia(CAH):normal pregnancy rate but reduced fertility rate[J].Clin Endocrinol(Oxf),2009,70:833-837.
[9] Chatziaggelou A,Sakkas EG,Votino R,et al.Assisted reproduction in congenital adrenal hyperplasia[J].Front Endocrinol(Lausanne),2019,10:723.
[10] Santos-Ribeiro S,Polyzos NP,Haentjens P,et al.Live birth rates after IVF are reduced by both low and high progesterone levels on the day of human chorionic gonadotrophin administration[J].Hum Reprod,2014,29:1698-1705.
[11] Lessey BA,Young SL.What exactly is endometrial receptivity [J].Fertil Steril.2019,111:611-617.
[12] Helleday J,Siwers B,Ritzén EM,et al.Subnormal androgen and elevated progesterone levels in women treated for congenital virilizing 21-hydroxylase deficiency[J].J Clin Endocrinol Metab,1993,76:933-936.
[13] Fanelli F,Belluomo I,Di Lallo VD,et al.Serum steroid profiling by isotopic dilution-liquid chromatography-mass spectrometry:comparison with current immunoassays and reference intervals in healthy adults[J].Steroids,2011,76:244-253.
[14] 卢琳,曾正陪,陆召麟,等.先天性肾上腺皮质增生症21羟化酶缺陷症合并妊娠的临床及生化特点[J].内科急危重症杂志,2010,16:13-16.
[15] 禹虹,边旭明,刘俊涛,等.21羟化酶缺乏症合并妊娠八例临床分析[J].中华妇产科杂志,2012,47:651-654.
基本信息:
中图分类号:R586;R714.8
引用信息:
[1]范融,王含必,邓成艳,等.失盐型21羟化酶缺乏症行体外受精-胚胎移植1例分析及文献复习[J].生殖医学杂志,2021,30(09):1244-1246.
2021-09-15
2021-09-15