生殖医学杂志

目的报告2018年度中国辅助生殖技术(ART)情况,为各项ART技术的使用提供依据。方法采用"中华医学会生殖医学分会(CSRM)数据上报系统",收集中国内地263家生殖中心上报的2018年ART数据,对ART技术使用情况进行横断面调查。结果 2018年CSRM数据上报系统共报告AID/AIH治疗周期105 610个、取卵周期323 938个、鲜胚移植周期147 129个、冻融胚胎移植(FET)周期254 012个、活胎总数为204 688个。63.75%不孕妇女年龄小于35岁。鲜胚移植周期临床妊娠率52.49%、活产率42.23%;FET周期临床妊娠率48.71%、活产率37.68%。ART并发症中,中重度OHSS发生率为1.42%,术后出血发生率为0.03%,术后盆腔感染发生率为0.01%,其他并发症发生率为0.04%。2018年IVF出生缺陷发生率为0.87%。结论本研究使用"CSRM数据上报系统"数据对ART现状特征进行描述分析,与2016、2017年比较情况基本一致,ART周期具有良好的妊娠结局。然而PGS/PGD周期、全胚冷冻的变化情况尚无明确结论,还需要结合实验室数据进行综合分析。

Objective:To analysis the Chinese assisted reproductive technology(ART) data in 2018 to provide evidence for utilization of various ART.Methods:The ART data of 263 reproductive centers in the mainland of China in 2018 were collected by "CSRM ART data reporting system". A cross-sectional survey of the usage status of ART technology was performed.Results:In 2018,the "CSRM data reporting system" reported 105 610 AID/AIH cycles, 323 938 oocyte retrieval cycles, 147 129 fresh embryo transfer cycles, 254 012 frozen-thawed embryo transfer(FET) cycles, and 204 688 newborns. 63.75% of infertile women were younger than 35 years old. The pregnancy rate and live birth rate of retrieval cycles were 52.49% and 42.23% respectively. The pregnancy rate and live birth rate of FET cycles were 48.71% and 37.68% respectively. Among ART complications, the incidence of moderate and severe OHSS was 1.42%,and the incidence of postoperative bleeding, postoperative pelvic infection and the other complications were 0.03%,0.01% and 0.04% respectively. The incidence of birth defects of IVF was 0.87%.Conclusions:This study used "CSRM data reporting system" data to describe and analyze the current status of ART. It is basically consistent with the comparison in 2016 and 2017,and the ART cycles obtained good pregnancy outcomes. However, no clear conclusions have been drawn on the changes of PGD/PGS cycle & whole embryo freezing cycle, and comprehensive analysis should be conducted by combining with laboratory data.