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1990年5～12月在北京东城区40～65岁妇女中进行了围绝经期流行病学调查。随机抽样得调查对象5000余名,应答率97.1％。共有5134名妇女进入分析,其中54.4％已绝经。绝经者中自然绝经占93.8％,手术绝经占5.4％。自然绝经平均年龄49岁。既往月经多,曾用甾体避孕药,肥胖及多次妊娠等与绝经晚有关;而吸烟及绝经前生活中发生重大事件可导致提早绝经。更年期症状不如西方妇女严重,与亚洲一些国家的研究结果接近,表明了种族和社会文化的不同对更年期症状的影响。产次、教育水平、绝经年龄、月经状况、哺乳、绝经时婚姻状态,以及生活中重大事件或环境变化等,均可以其特有方式影响更年期症状的轻重、出现早晚和持续时间。
Abstract：Due to the lack of information aboutthe menopause in China, an epidemiologic survey among perimenopausal women aged 40~65 was conducted in Beijing from May to December 1990. Over 5 000 women were selected by random sampling. An unified questionnaire was copmleted by face to face ynterviews. 5 134 women were included in the analysis. Among them 54. 4% were postmenopausal,10% in 40～49 age group,87. 8% in 50～59 and 99. 3% in 60～65 age group. The menopause in 93. 8% were natural menopause, 5. 4% after hysterectomy and 0. 8% after drug or radiation. The mean age at natural menopause is49(22～61) , not very different from other reports . Premature menopause before 4 0 was 3. 1 % . The incidence of menopausal symptoms varied between 4 6. 6 % ～1 0. 1 % . Irritability , sweating and hot flushing were the most frequent ones,but they were usually mild, only about 20% were severe, and other symptoms were severe in about 10%. Late menopause were related with heavy menstural bleeding , use of oral contraceptives, obesity and multigravida; while early menopause are related with smoking and accidents or happenings during premenopausal period. Only 4 women in this sample used estrogen replacement therapy for more than half a year, 0. 4% of the menopausal women. In this study, menopause following surgery, menopausal symptoms and hormone replacement therapy were all lower than that in western countries but similar to that in eastern countries.
1 Payer L. The menopause in various cultures. In: Burger H, Boulet M eds. A portrait of the menopause. Lancs UK: The Parthenon Publishing Co.,1991:3-23．
2 Schneider JT. The climacteric syndrome. In: Greenblatt AM ed. A modern approach to the perimenopausal years. New York, Walter de Gruyter, 1986:39-55．
3 Kupperman HS, Blatt MHG, Wiesvader H. Comparative clinical evaluation of estrogenic preparations by the menopausal and amenorrheal indices. J Clin Endocrinol, 1953,13:688．
4 Stanford JL, Hartge P, Brinton LA, et al. Factors influencing the age at natural menopause. J Chron Dis, 1987,40: 995．
5 Gindoff PR, Jewelewicz R. Reproductive potential in the old woman. Fertil Steril,1986,46:989．
6 Krailo MD, Pike MC. Estimation of the distribution of age at natural menopause from prevalence data. Am J Epidemiol, 1983,117:356．
7 Mckinlay SM, Brambilla DJ, Posner JG. The normal menopause transition. Maturitas, 1992,14:103．
8 Evelyn Anderson RN, Hamburage S, Liu JH, et al. Characteristics of menopausal women seeking assistance. Am J Obstet Gynecol, 1987,156:428．
9 deAloysio D, Fabiani AG, Mauloni M, et al. Analysis of the climacteric syndrome. Maturitas,1989,11:43．
10 Brenner PF. The menopausal syndrome. Obstet Gynecol, 1988,72[5 Suppl]:6S.
11 Lock M, Kanfert P, Hillert P. Cultural construction of the menopausal syndrome: the Japanese case. Maturitas, 1988, 10:317．
12 Bengtsson C. Aspects of hormone replacement therapy in the post-menopause. Maturitas, 1989, 11:35．
13 Jensen PR, Jensen J, Riis BJ, et al: Climacteric symptoms after oral and percutaneous hormone replacement therapy. Maturitas, 1987, 9:207．
14 Jannausch ML, Sowers MR. Consistency of perimenopausal estrogen use reporting by women in a population-based prospective study. Maturitas, 1992,14:161．
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引用信息:
[1]徐苓,赵珩,葛秦生.围绝经期的流行病学调查[J].生殖医学杂志,1993(01):23-27.