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2017, 01, v.26 82-86
AMH与卵巢储备功能及体外胚胎发育潜能的关系
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发布时间: 2017-01-15
出版时间: 2017-01-15
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摘要:

抗苗勒管激素(AMH)为转化生长因子β超家族的一员,是一种二聚糖蛋白。AMH作为单一指标预测卵巢储备功能,越来越受到重视。卵巢储备功能与女性的生育力及绝经年龄密切相关,准确、客观的评估女性的卵巢储备功能,预测其生育潜能及绝经年龄,利于育龄女性做好家庭生育计划及工作规划。现对AMH在预测卵巢储备功能、胚胎发育潜能的最新研究进展进行综述。

Abstract:

Anti-Müllerian hormone(AMH),apeptide homodimer consisting of two identical glycoprotein subunits,is a member of the transforming growth factor-super family.As a single ovarian reserve predicted marker,AMH is attracting more and more attention.Ovarian reserve function is closely related with female fertility and menopause age.Thus,accurate and objective assessment of women's ovarian reserve function plays important roles in making appropriate family and career plans.This article reviews the researches on AMH and the correlation with of ovarian reserve function and embryonic development potential.

参考文献

[1]Weenen C,Laven JS,Von Bergh AR,et al.Anti-Müllerian hormone expression pattern in the human ovary:potential implications for initial and cyclic follicle recruitment[J].Mol Hum Reprod,2004,10:77-83.

[2]Hampl R,najderováM,Mardei c′T.Antimüllerian hormone(AMH)not only a marker for prediction of ovarian reserve[J].Physiol Res,2011,60:217-223.

[3]de Vet A,Laven JS,de Jong FH,et al.Antimüllerian hormone serum levels:aputative marker for ovarian aging[J].Fertil Steril,2002,77:357-362.

[4]Tehrani FR,Solaymani-Dodaran M,Tohidi M,et al.Modeling age at menopause using serum concentration of antimullerian hormone[J].J Clin Endocrinol Metab,2013,98:729-735.

[5]American College of Obstetricians and Gynecologists Committee on Gynecologic Practice;Practice Committee of the American Society for Reproductive Medicine.Female agerelated fertility decline.Committee Opinion No.589[J].Obstet Gynecol,2014,123:719-721.

[6]Fleming R,Seifer DB,Frattarelli JL,et al.Assessing ovarian response:antral follicle count versus anti-Müllerian hormone[J/OL].Reprod Biomed Online.2015,31:486-496.

[7]Amer SA,Mahran A,Abdelmaged A,et al.The influence of circulating anti-Müllerian hormone on ovarian responsiveness to ovulation induction with gonadotrophins in women with polycystic ovarian syndrome:apilot study[J].Reprod Biol Endocrinol,2013,11:115.doi:10.1186/1477-7827-11-115.

[8]Durlinger AL,Gruijters MJ,Kramer P,et al.AntiMüllerian hormone attenuates the effects of FSH on follicle development in the mouse ovary[J].Endocrinology.2001,142:4891-4899.

[9]Broer SL,van Disseldorp J,Broeze KA,et al.Added value of ovarian reserve testing on patient characteristics in the prediction of ovarian response and ongoing pregnancy:an individual patient data approach[J].Hum Reprod Update,2013,19:26-36.

[10]Jamil Z,Fatima SS,Ahmed K,et al.Anti-Mullerian hormone:above and beyond conventional ovarian reserve markers[J].Dis Markers,2016,2016:5246217.

[11]魏晓丽,周远征,邓成艳,等.抗苗勒管激素与卵巢反应性及妊娠结局的相关研究[J].生殖医学杂志,2015,24:297-303.

[12]廖月婵,吴日然,柯玩娜,等.血清抗苗勒管激素水平检测在预测卵巢低反应中的应用价值[J].生殖医学杂志,2012,21:363-367.

[13]Arce JC,La Marca A,Mirner Klein B,et al.Antimüllerian hormone in gonadotropin releasing-hormone antagonist cycles:prediction of ovarian response and cumulative treatment outcome in good-prognosis patients[J].Fertil Steril,2013,99:1644-1653.

[14]Lekamge DN,Barry M,Kolo M,et al.Anti-Müllerian hormone as a predictor of IVF outcome[J/OL].Reprod Biomed Online,2007,14:602-610.

[15]Hazout A,Bouchard P,Seifer DB,et al.Serum antimüllerian hormone/müllerian-inhibiting substance appears to be a more discriminatory marker of assisted reproductive technology outcome than follicle-stimulating hormone,inhibin B,or estradiol[J].Fertil Steril,2004,82:1323-1329.

[16]Tremellen K,Kolo M.Serum anti-Mullerian hormone is a useful measure of quantitative ovarian reserve but does not predict the chances of live-birth pregnancy[J].Aust N Z J Obstet Gynaecol,2010,50:568-572.

[17]Smeenk JM,Sweep FC,Zielhuis GA,et al.Antimüllerian hormone predicts ovarian responsiveness,but not embryo quality or pregnancy,after in vitro fertilization or intracyoplasmic sperm injection[J].Fertil Steril,2007,87:223-226.

[18]Guerif F,Lemseffer M,Couet M,et al.Serum antimüllerian hormone is not predictive of oocyte quality in vitro fertilization[J].Ann Endocrinol(Paris),2009,70:230-234.

[19]Lehmann P,Vélez MP,Saumet J,et al.Anti-Müllerian hormone(AMH):a reliable biomarker of oocyte quality in IVF[J].J Assist Reprod Genet,2014,31:493-498.

[20]Ebner T,Sommergruber M,Moser M,et al.Basal level of anti-Müllerian hormone is associated with oocyte quality in stimulated cycles[J].Hum Reprod,2006,21:2022-2026.

[21]Dólleman M,Faddy MJ,van Disseldorp J,et al.The relationship between anti-Müllerian hormone in women receiving fertility assessments and age at menopause in subfertile women:evidence from large population studies[J].J Clin Endocrinol Metab,2013,98:1946-1953.

[22]Haikin Herzberger E,Ghetler Y,Tamir Yaniv R,et al.Time lapse microscopy is useful for elective single-embryo transfer[J].Gynecol Endocrinol,2016,2016:1-3.

[23]Martín J,Cervero A,Mir P,et al.The impact of nextgeneration sequencing technology on preimplantation genetic diagnosis and screening[J].Fertil Steril,2013,99:1054-1061.

[24]Rdgaard T,Heegaard PM,Callesen H.Non-invasive assessment of in-vitro embryo quality to improve transfer success[J/OL].Reprod Biomed Online,2015,31:585-592.

[25]Yamanaka M,Hashimoto S,Amo A,et al.Developmental assessment of human vitrified-warmed blastocysts based on oxygen consumption[J].Hum Reprod,2011,26:3366-3371.

[26]Loutradis D,Drakakis P,Kallianidis K,et al.Oocyte morphology correlates with embryo quality and pregnancy rate after intracytoplasmic sperm injection[J].Fertil Steril,1999,72:240-244.

[27]Ziebe S,Petersen K,Lindenberg S,et al.Embryo morphology or cleavage stage:how to select the best embryos for transfer after in-vitro fertilization[J].Hum Reprod,1997,12:1545-1549.

[28]Brodin T,Hadziosmanovic N,Berglund L,et al.Antimüllerian hormone levels are strongly associated with live-birth rates after assisted reproduction[J].J Clin Endocrinol Metab,2013,98:1107-1114.

[29]Kavoussi SK,Odenwald KC,Boehnlein LM,et al.Antimüllerian hormone as a predictor of good-quality supernumerary blastocyst cryopreservation among women with levels<1ng/mL versus 1-4ng/mL[J].Fertil Steril,2015,104:633-636.

[30]Sills ES,Collins GS,Brady AC,et al.Bivariate analysis of basal serum anti-Müllerian hormone measurements and human blastocyst development after IVF[J].Reprod Biol Endocrinol.,2011,9:153.doi:10.1186/1477-7827-9-153.

[31]Lin PY,Huang FJ,Kung FT,et al.Evaluation of serum anti-Mullerian hormone as a biomarker of early ovarian aging in young women undergoing IVF/ICSI cycle[J].Int J Clin Exp Pathol,2014,7:6245-6253.

[32]Szafarowska M,Molinska-Glura M,Jerzak MM.AntiMüllerian hormone concentration as a biomarker of pregnancy success or failure[J].Neuro Endocrinol Lett,2014,35:322-326.

[33]Kim JH,Lee JR,Chang HJ,et al.Anti-Müllerian hormone levels in the follicular fluid of the preovulatory follicle:a predictor for oocyte fertilization and quality of embryo[J].J Korean Med Sci,2014,29:1266-1270.

[34]陈艺,刘海鹏,李苏萍,等.抗苗勒氏管激素水平对IVF-ET妊娠结局的预测价值评估[J].生殖医学杂志,2016,25:522-527.

[35]Fanchin R,Mendez LDH,Frydman N,et al.Anti-Müllerian hormone concentrations in the follicular fluid of the preovulatory follicle are predictive of the implantation potential of the ensuing embryo obtained by in vitro fertilization[J].J Clin Endocrinol Metab,2007,92:1796-1802.

[36]Hattori Y,Sato T,Okada H,et al Comparison of follicular fluid and serum anti-Mullerian hormone levels as predictors of the outcome of assisted reproductive treatment[J].Eur J Obstet Gynecol Reprod Biol,2013,169:252-256.

[37]Nelson SM,Yates RW,Fleming R.Serum anti-Müllerian hormone and FSH:prediction of live birth and extremes of response in stimulated cycles--implications for individualization of therapy[J].Hum Reprod,2007,22:2414-2421.

[38]La Marca A,Nelson SM,Sighinolfi G,et al.Anti-Müllerian hormone-based prediction model for a live birth in assisted reproduction[J/OL].Reprod Biomed Online,2011,22:341-349.

[39]Mutlu MF,Erdem M,Erdem A,et al.Antral follicle count determines poor ovarian response better than anti-Müllerian hormone but age is the only predictor for live birth in in vitro fertilization cycles[J].J Assist Reprod Genet,2013,30:657-665.

基本信息:

中图分类号:R714.8

引用信息:

[1]黄佳语,高颖.AMH与卵巢储备功能及体外胚胎发育潜能的关系[J].生殖医学杂志,2017,26(01):82-86.

发布时间:

2017-01-15

出版时间:

2017-01-15

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