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辅助生殖技术(ART)近年来已帮助数百万不孕不育患者解决了孕育难题。然而,随着ART的日益普及,其近远期安全性问题引起生殖医学领域学者的关注和重视。有研究发现,经ART助孕人群的围产期并发症和不良妊娠结局的发生率比自然妊娠人群高。通过ART技术孕育的子代在出生缺陷、神经系统发育及心血管系统健康等方面的风险也被广泛讨论。这些风险的增加,一方面可能来源于不孕不育患者自身的不孕因素,另一方面可能与ART过程中的技术操作有关。未来,需进一步优化ART的诊疗方案,加强母胎监测及管理,从而提升ART妊娠的安全性及子代健康水平。
Abstract:In recent years, assisted reproductive technology(ART) has helped millions of infertile patients overcome their fertility challenges. However, with the increasing popularity of ART,concerns and attention have been paid by scholars in the field of reproductive medicine regarding its short-and long-term safety issues. Some studies have found that the incidence of perinatal complications and adverse pregnancy outcomes is higher in ART-assisted pregnancy groups compared to natural pregnancy groups. The risks in offspring associated with ART technology, such as birth defects, nervous system development, and cardiovascular system health, have also been widely discussed. The increase of these risks may be attributed to the infertility factors of the infertile patients themselves on one hand, and to technical operations during the ART process on the other hand. In the future, it is necessary to further optimize the diagnosis and treatment protocols of ART,strengthen maternal-fetal monitoring and management, and thereby improve the safety of ART pregnancy and the health level of offspring.
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基本信息:
中图分类号:R714.8
引用信息:
[1]黄玉晗,李晨歌,霍晓博,等.辅助生殖技术助孕人群妊娠结局和子代健康的研究进展[J].生殖医学杂志,2026,35(05):696-701.
基金信息:
河北省自然科学基金(H2021206377)
2026-05-15
2026-05-15