nav emailalert searchbtn searchbox tablepage yinyongbenwen piczone journalimg journalInfo journalinfonormal searchdiv searchzone qikanlogo popupnotification paper paperNew
2023, 07, v.32 1070-1077
4例子宫脂肪平滑肌瘤临床病理分析并文献复习
基金项目(Foundation):
邮箱(Email):
DOI:
发布时间: 2023-07-15
出版时间: 2023-07-15
移动端阅读
摘要:

子宫脂肪平滑肌瘤是子宫肌瘤的一种罕见变异类型,由不同比例的成熟平滑肌细胞和成熟脂肪细胞组成,不伴有出血、坏死或细胞结构异型性,术前极易误诊为其他妇科肿瘤。充分了解子宫脂肪平滑肌瘤的临床病理特征有助于早期诊断和临床干预。本文分析了我院2021年诊断为子宫脂肪平滑肌瘤的4例病例的临床特征及病理特点,结合既往文献对子宫脂肪平滑肌瘤的病因、影像学特点、病理特点、疾病恶变潜能、与代谢性疾病及雌激素的关系等方面进行了归纳总结,以期为子宫脂肪平滑肌瘤的诊断及其今后的研究方向提供新思路。

Abstract:

Uterine lipoleiomyoma is a rare variation of uterine leiomyoma, consisting of mature smooth muscle cells and mature adipose cells in varying proportions, without bleeding, necrosis or cellular structural heterogeneity. It is easy to be misdiagnosed as other gynecological tumors before surgery. Fully understanding the clinical and pathological characteristics of uterine lipoleiomyoma is helpful for early diagnosis and clinical intervention. This paper analyzed the clinical and pathological characteristics of 4 patients who were diagnosed as uterine lipoleiomyoma in our hospital in 2021,and summarized the etiology, radiologic characteristic, pathological features, disease malignancy potential, the relationship with metabolic diseases and estrogen by referring to the previous literature, in order to provide new ideas for the diagnosis and future research directions of uterine lipoleiomyoma.

参考文献

[1] Chandawale SS,Karia KM,Agrawal NS,et al.Uterine lipoleiomyoma and lipoma:a rare unique case report with review of literature[J].Int J Appl Basic Med Res,2018,8:193-195.

[2] Wilke S,Benson J,Roller L.Uterine lipoleiomyoma:case report and review of the literature[J].Radiol Case Rep,2022,17:954-958.

[3] 刘婷婷,王翔宇,韩毅,等.子宫脂肪平滑肌瘤临床及病理学特征探讨(附1例报告及文献复习)[J].青岛大学学报(医学版),2020,56:109-111.

[4] Yadav S,Maheswari B,Sagar N,et al.Broad ligament lipoleiomyoma masses:two curious cases masquerading as ovarian carcinomas[J].Sultan Qaboos Univ Med J,2017,17:e477-e480.

[5] 王睿,沙仁高娃.卵巢早衰相关发病因素的病例对照研究[J].医学信息,2022,35:95-98.

[6] Fattahi N,Moeini A,Morani AC,et al.Fat-containing pelvic lesions in females[J].Abdom Radiol(NY),2022,47:362-377.

[7] Jamoulle J F,Brisbois D.Lipoleiomyoma:rare tumor of the uterus[J].Rev Med Liege,2020,75:137-139.

[8] Kiuchi K,Hasegawa K,Ochiai S,et al.Liposarcoma of the uterine corpus:a case report and literature review[J].Gynecol Oncol Rep,2018,26:78-81.

[9] Rampersad FS,Verma S,Diljohn J,et al.Uterine lipoleiomyoma presenting with pelvic pain in a post-menopausal woman[J].Cureus,2021,13:14929.

[10] Karaman E,Cim N,Bulut G,et al.A case of giant uterine lipoleiomyoma simulating malignancy[J].Case Rep Obstet Gynecol,2015,2015:926961.

[11] Fujiwaki R,Ohnuma H,Miura H,et al.Uterine lipoleiomyoma in an elderly patient:a case report[J].Arch Gynecol Obstet,2008,277:471-474.

[12] Sun D,Yang P,Liu Y,et al.Fallopian tube lipoleiomyoma with degeneration:a case report and literature review[J].Int J Clin Exp Pathol,2020,13:2163-2168.

[13] Mosca L,Schiattarella A,Cafiero A,et al.An impressive uterine mass:a case of a lipoleiomyoma[J].J Obstet Gynaecol Can,2022,44:1-2.

[14] Akbulut M,Gündo■an M,Y?rüko■lu A.Clinical and pathological features of lipoleiomyoma of the uterine corpus:a review of 76 cases[J].Balkan Med J,2014,31:224-229.

[15] Schaefer SL,Strong AL,Bahroloomi S,et al.Large intraperitoneal lipoleiomyoma in a pre-menopausal woman:a case report[J].World J Surg Oncol,2021,19:144.

[16] Di Spiezio Sardo A,Gencarelli A,Vieira MDC,et al.Differentiating a rare uterine lipoleiomyoma from uterine perforation at hysteroscopy:a scary story[J].J Minim Invasive Gynecol,2020,27:9-10.

[17] Alsaif JM,Alali ZS,Elsharkawy T,et al.Uterine lipoleiomyoma:a case report and review of literature[J].Cureus,2021,13:20297.

[18] Mignogna C,Di Spiezio Sardo A,Spinelli M,et al.A case of pure uterine lipoma:immunohistochemical and ultra-structural focus[J].Arch Gynecol Obstet,2009,280:1071-1074.

[19]Terada T.Huge lipoleiomyoma of the uterine cervix[J].Arch Gynecol Obstet,2011,283:1169-1171.

[20]■,JeleńM,Kosiński M,et al.Research on genesis of adipocytic metaplasia in uterine fibroids[J].Pol J Pathol,2015,66:403-409.

[21] Mok H,Feng J,Hu W,et al.Decreased serum estrogen improves fat graft retention by enhancing early macrophage infiltration and inducing adipocyte hypertrophy[J].Biochem Biophys Res Commun,2018,501:266-272.

[22] 岳君秋,张杨鸽龄,叶志英,等.子宫脂肪平滑肌瘤17例临床病理分析[J].湖北民族学院学报(医学版),2012,29:38-42.

[23] Yuan Y,Chen L,Zhao T,et al.Pathogenesis,diagnosis and treatment of uterine lipoleiomyoma:a review[J].Biomed Pharmacother,2021,142:112013.

[24] Bosoteanu M,Vod RI,Orasanu CI,et al.A case of giant mesenchymal uterine tumor:lipoleiomyoma[J].Am J Case Rep,2022,23:934913.

[25] McDonald AG,Dal Cin P,Ganguly A,et al.Liposarcoma arising in uterine lipoleiomyoma:a report of 3 cases and review of the literature[J].Am J Surg Pathol,2011,35:221-227.

[26] Rasmussen T,Sanchirico P,Pfeiffer D.Uterine lipoleiomyoma in the context of adenocarcinoma[J].J Clin Imaging Sci,2020,10:82.

[27] Oh SR,Cho YJ,Han M,et al.Uterine lipoleiomyoma in peri- or postmenopausal women[J].J Menopausal Med,2015,21:165-170.

[28] Scurry J,Hack M.Leiomyosarcoma arising in a lipoleiomyoma[J].Gynecol Oncol,1990,39:381-383.

[29] Wang X,Kumar D,Seidman JD.Uterine lipoleiomyomas:a clinicopathologic study of 50 cases[J].Int J Gynecol Pathol,2006,25:239-242.

[30] Kiyokoba R,Yagi H,Yahata H,et al.Tumor-to-tumor metastasis of poorly differentiated gastric carcinoma to uterine lipoleiomyoma[J].Case Rep Obstet Gynecol,2015,2015:352369.

[31] Sakai S,Morinaga Y,Koshiba A,et al.Unexpected tumor-to-tumor metastasis of synovial sarcoma within leiomyoma:a case report and literature review[J].J Obstet Gynaecol Res,2020,46:1216-1223.

基本信息:

中图分类号:R737.33

引用信息:

[1]赫艳玲,何智伟,刘潇婧,等.4例子宫脂肪平滑肌瘤临床病理分析并文献复习[J].生殖医学杂志,2023,32(07):1070-1077.

发布时间:

2023-07-15

出版时间:

2023-07-15

检 索 高级检索

引用

GB/T 7714-2015 格式引文
MLA格式引文
APA格式引文