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2022, 04, v.31 435-440
短效口服避孕药在40岁以上高FSH患者IVF/ICSI中的短时应用分析
基金项目(Foundation): 江苏省高校优势学科建设工程(JX10231802); 国家自然科学基金(81501225); 江苏省自然科学基金(BK20151030); 江苏省卫健委项目(M2020097)
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发布时间: 2022-04-15
出版时间: 2022-04-15
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摘要:

目的 探讨避孕药短时应用结合微刺激方案在40岁以上高FSH患者体外受精-胚胎移植中的促排卵效果及周期结局。方法 回顾性分析2016年1月至2020年10月在南京医科大学第一附属医院生殖中心行克罗米芬联合HMG微刺激IVF或ICSI助孕的40岁以上患者的临床资料,共227个周期。其中,基础FSH≥20 U/L者予口服避孕药(OCP)短时预处理,为OCP组(n=103);而10 U/L0.05)。结论 对40岁以上高龄FSH>20 U/L无法常规启动IVF促排卵的患者,可行OCP短时预处理,可有效降低FSH和LH水平,结合微刺激方案能有效帮助部分患者获得妊娠。

Abstract:

Objective:To investigate the effect and outcome of short-term application of contraceptives combined with micro stimulation protocol during IVF-ET in patients over 40 years old with high FSH.Methods:The clinical data of patients(227 cycles) aged >40 years who underwent IVF/ICSI with clomiphene and micro stimulation protocol in of Reproductive Medicine Center, the First Affiliated Hospital of Nanjing Medical University from January 2016 to October 2020 were retrospectively analyzed. Among them, the patients with basal FSH≥20 U/L had short-term pretreatment with oral contraceptive(OCP) as OCP group(n=103),and the patients with 10 U/L0.05).Conclusions:For patients over 40 years old with FSH>20 U/L who are unable to initiate induction ovulation for IVF,OCP short-term pretreatment can effectively reduce their FSH and LH levels. Combined with micro stimulation protocol, it can effectively help some patients to obtain pregnancy.

参考文献

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基本信息:

中图分类号:R714.8

引用信息:

[1]蒋春艳,鲁南,张园,等.短效口服避孕药在40岁以上高FSH患者IVF/ICSI中的短时应用分析[J].生殖医学杂志,2022,31(04):435-440.

基金信息:

江苏省高校优势学科建设工程(JX10231802); 国家自然科学基金(81501225); 江苏省自然科学基金(BK20151030); 江苏省卫健委项目(M2020097)

发布时间:

2022-04-15

出版时间:

2022-04-15

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