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21-羟化酶缺陷是由肾上腺合成皮质醇所需的酶缺乏所致，临床上21-羟化酶缺陷患者常常存在卵泡生长不佳、子宫内膜容受性改变，给患者生育带来困难。本文报道1例辅助生殖成功的21-羟化酶缺陷病例，我们发现在辅助生殖治疗中对糖皮质激素的剂量调整和使用多种方法检测类固醇激素的变化十分关键。提升21-羟化酶缺陷患者的生育力，需要内分泌科、妇科、产科等多学科协作，密切随访，不断总结临床经验。
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基本信息:
中图分类号:R714.8
引用信息:
[1]程凤,颜廷会,熊巍.21-羟化酶缺陷反复IVF失败后成功妊娠1例[J].生殖医学杂志,2024,33(04):517-520.
基金信息:
北京协和医院中央高水平临床科研专项(22-PUMCH-A-235)
2024-04-15
2024-04-15